Aims

• To introduce some of the current challenges in structural bioinformatics.

Objectives

After this lecture you will:

• understand the objectives of comparative modelling, fold recognition and secondary structure prediction;
• be aware of approaches to comparative modelling, fold recognition and secondary structure prediction.

Supplementary Material

The lecture handout, featuring some of the lecture slides, is available on-line.
Download PDF (33k)

Pages 39-50 and chapter 5 of the course text (Introduction to Bioinformatics, by Arthur M. Lesk) contain material relevant to the lectures on protein structure.

Rob Russell has written A Guide to Structure Prediction that includes practical advice and links to useful software.