Graham Kemp > Teaching > Bioinformatics III |
After this lecture you will:
Michael Levitt has produced some useful lecture slides that include descriptions of the protein folding problem, molecular simulation and structure prediction by energy minimisation.
The lecture handout, featuring some of the lecture slides, is
available on-line.
Download PDF
The ab initio protein structure prediction algorithm introduced in this lecture is described in:
Simons, K.T., Kooperberg, C., Huang, E. and Baker, D. (1997) Assembly of Protein Tertiary Structures from Fragments with Similar Local Sequences using Simulated Annealing and Bayesian Scoring Functions. J. Mol. Biol., 268, 209-225. (Journal web site)